Which airlines fly direct between Lisbon and Santiago?

Airlines operating direct flights include TAP Air Portugal, Ryanair, LATAM Airlines, Sky Airline.

What is the cheapest fare for this route?

Recorded one-way fares on Prymeo start from as low as $669 depending on season and advance booking.

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Verified Route Guide

Flights from Lisbon to Santiago

Q: How long is the flight from Lisbon to Santiago?

The average nonstop flight time from Lisbon (LIS) to Santiago (SCL) is approximately 12h 45m covering a distance of 10235 km.

Humberto Delgado Airport (LIS) → Comodoro Arturo Merino Benítez (SCL)

Fares From$669

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Flight Time

12h 45m

Nonstop average

Distance

10235 km

Air route corridor

Best Time to Fly

Year-Round (Best rates booked 3-5 weeks ahead)

Pleasant weather

Extra Fees

$0.00

Zero commission

Route Overview: Lisbon to Santiago

Cheap flights from Lisbon (LIS) to Santiago (SCL). Compare TAP Air Portugal fares from $669 with 0% fees on Prymeo.

Prymeo aggregates real-time flight availability directly from both low-cost carriers and legacy full-service airlines. When searching for tickets between Humberto Delgado Airport and Comodoro Arturo Merino Benítez, our technology checks multiple booking systems in parallel so you never miss a flash sale or promotional discount.

Direct Carriers on This Corridor

TAP Air Portugal

Ryanair

LATAM Airlines

Sky Airline

Quick Flight Facts & Corridor Specifications

Live Verified Data

Route Corridor	Lisbon (LIS) to Santiago (SCL)
Flight Distance	10,235 kilometers / 6,360 miles
Average Flight Duration	12h 45m (nonstop)
Starting Fare	From $669 (0% added booking fees)
Operating Airlines	TAP Air Portugal, Ryanair, LATAM Airlines, Sky Airline
Optimal Travel Season	Year-Round (Best rates booked 3-5 weeks ahead)

Return Flight Route

Santiago (SCL) to Lisbon (LIS)

Nonstop return tickets from $669 · 0% booking markup

View Return Leg

Frequently Asked Questions About This Route

How long is the flight from Lisbon to Santiago?

The nonstop flight takes approximately 12h 45m, traversing 10235 km.

How far in advance should I book my flight?

For the best rates, we recommend booking between 3 to 6 weeks before your desired departure date, particularly during peak summer and holiday seasons.